A protective mechanism of probiotic Lactobacillus against hepatic steatosis via reducing host intestinal fatty acid absorption

A protective mechanism of probiotic Lactobacillus against hepatic steatosis via reducing host intestinal fatty acid absorption

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Liver disease: Beneficial bacteria divert dietary fats Intestinal bacteria that consume common fatty acids could help protect their hosts against non-alcoholic fatty liver disease (NAFLD).The accumulation of lipids over the course St Ishmaels CC Club Shop of NAFLD can produce serious inflammation and ultimately lead to liver failure.The gut microbiome plays a prominent role in metabolic health and South Korean researchers led by Hui-Young Lee of Gachon University, Incheon, and Jae-Hak Park of Seoul National University, Seoul, have identified a bacterial species that could help prevent NAFLD.They found that Lactobacillus rhamnosus GG can absorb oleic acid, a fatty acid commonly found in the human diet.Transplantation of these bacteria into high-fat diet-fed mice resulted in weight loss and Respirators reduced fat accumulation in the liver.

These findings providing a new mechanistic insight into the impact of certain probiotic species on NAFLD.